A neo cassette flanked by two FRT sites was inserted upstream of exon 3 and two loxP sites were inserted to flank exon 3. Flp-mediated recombination removed the selection cassette, leaving exon 3 floxed. (J:166881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count