The targeting vector contained an cre/ERT2 cassette inserted at the start codon of the Pdgfra locus. The cre cassette was followed by a FRT-flanked neo cassette, which was removed by flp-mediated excision after germline transmission. (J:263983)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count