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A loxP-tdTomato-Stop-polyA-loxP-diptheria toxin A (DTA) cassette was introduced to mouse BAC (MSMg01-143H02) containing the Hpgds gene exon2 downsterem and in frame with the start codon. In presence of cre recombinase, the tdTomato reporter cassette is excised, allowing expression of DTA and ablation of the expressing cells. Thtee founders animals were initialy created, but only one line was maintained. Only one line of this strain (line 1) is available. (J:265285)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
