The transgenic construct was designed with a human keratin 14 promoter driving co-expression of both a turbo red fluorescent protein (tRFP) and a suicide gene, herpes simplex virus (HSV) thymidine kinase (TK), separated by a P2A peptide plus a neomycin selection cassette. The neomycin cassette was later removed. tRFP is a fast-maturing destabilized red (orange) fluorescent protein. (J:264089)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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