The transgenic construct was designed with a mouse keratin 8 promoter followed by a rabbit beta-globin intron driving co-expression of both a turbo green fluorescent protein (tGFP) and a suicide gene, chimpanzee diphtheria toxin receptor, separated by a P2A peptide plus a hygromycin selection cassette. The hygromycin cassette has been removed. tGFP is a fast-maturing short half-life turbo green fluorescent protein. (J:264089)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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