A construct, which were flanked by attP sites, contained (5' to 3') upstream loxP site, first frt site, adenovirus splice acceptor (SA), tau-lacZ (tZ) reporter gene equipped at its C terminus with a flag tag, second frt site and a reverse-oriented EM7-neo positive selection cassette, including a bovine growth hormone polyadenylation signal. Downstream of the second attP site there was a reverse-oriented Pgk1 promoter, a third frt site all inserted into upstream of exon 2 into intron 1. A downstream loxP site was inserted into exon 2 downstream of 3' UTR. (J:264526)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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