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A single G-to-A base change was introduced in the CpG island in intron 1 of the Igf2 gene splice variant with the most upstream exon 1. LoxP sites were inserted around the CpG island and an FRT flanked neomycin resistance gene cassette was inserted via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:265506)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
