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A cassette containing a modified CreERT2-pA-Frt-Ampicillin-Frt was inserted in the first coding ATG of exon 2 into a bacterial artificial chromosome (BAC) containing the Ntrk2 mouse locus (RP23-391J8) deleting the entire coding region of exon 2. Purified BAC cDNA was purified and injected into pronuclei of B6D2F1/N oocytes or prepared for intracytoplasmic sperm injection (ICSI). Both methods produced transgenic offspring. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:265202)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
