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The transgene is designed with a bidirectional tetracycline operator (tetO; also called tetracycline-responsive element (TRE, TetRE) or tet-operator), Bi-L-Tet, located between two cytomegalovirus (CMV) minimal promoters in the opposite orientation. One CMV promoter drives expression of the murine DEK oncogene (DNA binding) gene (Dek) followed by a polyA signal, while the other CMV reporter drives expression of a luciferase (luc) reporter followed by a simian virus 40 (SV40) polyadenylation (polyA) signal. (J:261249)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
