The targeting vector is designed to insert a loxP-flanked PGK-NeoR/KanR cassette on one side, and a loxP site on the other side of exons 6-7. Exons 6 and 7 encode the SAND domain. (J:258694)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count