The human cDNA was placed behind a minimal CMV promoter and five tetracycline responsive elements. The construct was microinjected into the pronuclei of FVB/NCr embryos. The exogenous gene will only be expressed (in a tetracycline/doxycycline controllable manner) if mice containing this allele are crossed with mice containing a tTA or rtTA allele. (J:265381)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NCr
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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