The mouse gene, isolated from a BAC, was modified by the in-frame insertion into exon 2 of the EGFP gene and SV40 poly(A) sequences after codon 19. The resulting transgene was microinjected into the proneclei of fertilized eggs. This transgene drives the expression of the fluorescent protein from the paired box 2 promoter. (J:73896)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F1
--
Insertion
--
--
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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