The transgene construct comprises the following elements: the tetracycline response element (TRE) containing promoter tetO, the rat beta double C2 cDNA, sequence for a C-terminal Myc-His tag, an IRES, the EGFP fluorescent reporter gene, and poly(A) signal sequence. This allele, when co-expressed with an rTA or rtTA expressing allele, will express the inserted genes in a tetracycline/doxycycline inducible manner. (J:264812)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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