ENU-induced A to G transition at base pair 124,732,435 (v38) on chromosome 6, or base pair 6,275 in the GenBank genomic region NC_000072. The mutation corresponds to residue 392 in the mRNA sequence NM_013545 within exon 3 of 16 total exons. The mutation results in a tyrosine to cysteine substitution at position 64 (Y64C) in variant 1 of the SHP1 protein. (J:264807)