The targeting construct contains loxP sites flanking exons 1 and 2. An FRT-flanked neomycin cassette is present in the construct, however, Flp-mediated recombination removed the cassette. (J:229795)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count