Log In|Sign Up
EN
The construct comprises the human cytomegalovirus immediate early (CMV IE) promoter, an SV40 intron, the human interleukin 4 cDNA, and the SV40 poly(A) signal. The construct was microinjected into NOG (NOD.Cg-Prkdcscid Il2rgtm1Sug/ShiJic) fertilized eggs at the pronuclear stage. Line 17 showed intermediate expression of the exogenous gene and stable germline transmission. (J:248533)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
