A loxP site was inserted 5 of exon 4 and a loxP-flanked neomycin resistance gene cassette was inserted 3 of exon 6. The selection cassette was removed via cre-mediated recombination leaving exons 4-6 floxed. (J:264273, J:298625)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count