CRISPR/Cas9 mediated mutagenesis created a T to G change resulting in an aspartate substitution for tyrosine at amino acid 381. mRNA level in liver tissue is not affected and protein level is similar to wild-type. (J:262204)
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CRISPR/Cas9 mediated mutagenesis created a T to G change resulting in an aspartate substitution for tyrosine at amino acid 381. mRNA level in liver tissue is not affected and protein level is similar to wild-type. (J:262204)