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EN
The targeting vector contains from 5' to 3' a loxP site, cDNA encoding the transmembrane and cytosolic domains of human SIGLEC16 gene, a human growth hormone polyadenylation sequence and an FRT-site flanked neo cassette inserted into exon 4. A second loxP site is inserted downstream of exon 5. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed exons 4-5. (J:274372)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
