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An inversion was generated between the regions targeted by sgRNAs 5'-GAGATTCTACTCCTAAGCCC-3' and 5'-ATTCCCCGGGAAATAGCCCA-3', using CRISPR/Cas9 technology. This CpG island contains a bidirectional promoter for Hoxd1 and Haglr and also encompasses the first exons of both genes. (J:252916)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
