Exon 2 was flanked by loxP sites and a FRT-flanked neo cassette was inserted upstream of the first loxP site via homologous recombination. Flp-mediated recombination removed the selection cassette. (J:264147)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count