CRISPR/cas9 endonuclease mediated genome editing is used to insert a 2A-EGFP ssDNA (encoding a viral 2A oligopeptide that mediates ribosomal skipping and an enhanced green fluorescent protein gene) with 55 bp homology arms into the stop codon of the gene. (J:280123)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count