The transgene contains the following elements: the CMV promoter, coding sequence for human prostaglandin-endoperoxide synthase 1, sequence for a 10 amino-acid transmembrane linker derived from human rhodopsin, prostaglandin I2 synthase coding sequence and PGH (porcine growth hormone) pA signal. The construct was microinjected into fertilized oocytes. The promoter drives ubiquitous expression of the chimeric protein. (J:260161)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
2
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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