The second coding exon was flanked by loxP sites. An frt-flanked neomycin selection cassette was inserted between the loxP site and the 5 end of exon 2. (J:263474)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count