The targeting construct introduced into the locus a CAG promoter, floxed STOP cassette, human Kir2.1 coding sequence fused to the mCherry reporter gene, a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability) and polyadenylation sequence. (J:245007)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count