The transgene comprises the mouse promoter (including the last exon of the Myh7 and the first three exons of the Myh6 gene), the single coding exon of the human angiotensin II receptor type 1 gene and SV40 poly(A) signal. The mouse promoter drives expression of the human gene in the myocardium. (J:59935)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3H x C57BL/6
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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