A 24 kb BamHI fragment of cosmid Mann 4.2, containing allele HLA-DRA1*0101 and 5' and 3' flanking sequence, and clone 11, a full-length DRB1*1501 allele cosmid encompassing extensive flanking 5' and 3' regulatory sequence, were microinjected into oocytes. Mice with this transgene express the human HLA-DR15 serotype. (J:96561)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x CBA)F2
--
Insertion
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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