A construct containing 6 NFkappaB-responsive elements (RE) from the CMV (immediate early) promoter were placed upstream of a basal SV40 promoter. This drives ubiquitous basal expression of a modified firefly luciferase cDNA. LPS and TNFalpha induce increased expression of the reporter. (J:147112)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
BALB/cJ
--
Insertion
--
--
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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