The transgene was comprised of a 600-bp rat insulin II promoter (RIP) fragment and the 3-UTR of the mouse MHC Ea-II gene, including the polyadenylation sequence, flanking a 676-bp Sma/Bgl I fragment of the human IAPP cDNA, containing the entire coding sequence of the gene. Only one line, 25-3 was studied further. (J:263024)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x DBA
--
Insertion
--
1
--
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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