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The complete 6,982 bp of coding sequence, including 250 nucleotides upstream of the transcriptional start site and 321 nucleotides following the 3'-end of the transcript, was flanked by loxP sites. A FRT-flanked neomycin cassette was inserted downstream of the coding sequence but upstream of the second loxP site. Cre-mediated recombination removed the entire floxed region. qRT-PCR confirmed absence of transcripts in various organs. (J:260021)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
