LoxP sites were inserted to flank exons 15-18. An frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. Exons 15-18 encode the kinase domain. (J:250330)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count