CRISPR/cas9 endonuclease mediated genome editing is used to delete 13 bp (nucleotides 1570 to 1582) creating a null allele. (J:101977)
Basic Information
B6(SJL)-Apoetm1.1(APOE*4)Adiuj/J
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count