Exon 4 was flanked by loxP sites and a FRT-flanked neomycin selection cassette was inserted downstream of the second loxP site. Flp-mediated recombination removed the selection cassette, leaving exon 4 floxed. (J:245025)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count