A loxP site was inserted upstream of exon 11 and a FRT-flanked PGK-neomycin resistance cassette and a second loxP site were inserted downstream of exon 12. Flp-mediated recombination removed the selection cassette, leaving exons 11-12 floxed. (J:262206)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count