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A fragment of mouse genomic sequence from 453 bp upstream of the transcription start site of the Col11a2 gene to 380 bp downstream (the former being promoter and the latter being 5' UTR sequence), was cloned upstream of a construct containing SV40 intronic sequence, the lacZ reporter gene and SV40 poly(A) signal. A 2.3 kb DNA fragment representing most of the first intron of Col11a2 was inserted downstream of the poly(A) signal. This construct was microinjected into the pronuclei of fertilized eggs from F1 C57BL/6 C3H hybrid mice. (J:35420)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
