A targeting vector containing, from 3' to 5': a single residual FRT site, an Engrailed 2 (En2) intron and H2B/Venus fusion cassette, a Rox-flanked beta-actin-NEO-pA cassette, and a loxP site was inserted upstream of exon 2. A second loxP site was inserted downstream of exon 2. Exon 2 contains the ATG start codon. (J:101977, J:264612)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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