The mammary gland specific rat promotor drives expression of the human gene. To distinguish the exogenous transgene-encoded peptide from the endogenous peptide, the human peptide was engineered with three C-terminal hemagglutinin (HA) epitope tags. Three transgenic lines were established, with line number 3 chosen for further experiments. (J:218834)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count