ES cells from Shank3tm1.1Bux mice were retargeted to carry a third loxP site downstream of exon 22. The allele contains a loxP site inserted upstream of exon 4, a second loxP site inserted downstream of exon 9, and a third loxP site downstream of exon 22. Cre-mediated recombination removed the exons 4-22. (J:175320, J:270363)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Intragenic deletion
--
1
5
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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