The transgene is composed of an N-terminal mitochondrial targeting pre-sequence (derived from human cytochrome c oxidase subunit VIII [COX8A]), fused to a far-red fluorescent protein, mKate2. The fusion protein cDNA sequence was placed downstream of the CMV enhancer/chicken beta-actin (CAG) promoter. (J:257641)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count