A loxP site was inserted upstream of exon 2 and floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neomycin cassette, leaving exons 2 and 3 floxed. (J:247734)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count