The targeting construct introduced a loxP site and gene trap cassette upstream of exon 2. A neomycin resistance cassette was inserted between exon 2 and 3. An additional loxP site was introduced downstream of exon 3. (J:262080)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count