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CRISPR/cas9 genome editing used guide RNAs to target intron 1 of the Gt(ROSA)26Sor locus. Oligonucleotide donor DNAs were created encoding a duel landing pad flanked by the heterologous attP attachment sites - specifically a 48 bp Bxb1 attP-GT sequence, a 240 bp spacer of native Gt(ROSA)26Sor sequence and a 48 bp Bxb1 attP-GA sequence. (J:322700)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
