CRISPR/cas9 mediated HDR using a single stranded oligo, which included homology arms, is used to insert a Bxb1 attP-GT site (48 bp) into intron 1 of the ROSA26 locus. (J:322700)
Basic Information
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count