LoxP sites have been inserted into introns 1 and 3. A single FRT site in the 3' untranslated region (UTR), just 5' of the Pgk-neo cassette, marks the former site of a neomycin selection cassette that has been deleted by flp recombinase. Crossing mice bearing this allele with Cre recombinase-expressing mice will delete exons 2 and 3, which contain the entire homeodomain. (J:94077, J:260050)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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