The transgene consists of the full-length mouse cDNA under the control of the mouse alpha myosin heavy chain promoter. This allele is one of three that showed germline transmission (the others being lines 8 and 11) and was chosen for futher study. Immunoblot assays indicate that the expression from this allele is around 20-fold higher than expression from the endogenous gene. (J:262067)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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