The transgenic construct is of a CX1 promoter (consisting of a portion of the beta-actin and CMV enhancer sequences), a loxP-flanked EGFP/Stop polyA cassette and the human NOX1 cDNA, This high copy founder line (Tg1) incorporates more than 50 copies of the transgene. (J:127882)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count