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A C-to-T nonsense mutation was introduced into the germline at posiition 451 [c.451C>T (CGA>TGA)]. This mutation is predicted to alter codon 151 from arginine to a stop codon (p.R151X). A loxP-flanked neomycin selection cassette was removed in ES cells prior to making chimeric mice. (J:261869)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
