LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank the promoter and the first two exons of the gene. The neomycin selection cassette was deleted by FLP-mediated recombination in mice. (J:232636)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count