Exon 1 was deleted by Cre-mediated recombination of flanking loxP sites. RT-PCR analysis confirmed that Cre-mediated recombination led to a loss of mRNA expression in the liver and brain of homozygous mutant mice. (J:243657)
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Exon 1 was deleted by Cre-mediated recombination of flanking loxP sites. RT-PCR analysis confirmed that Cre-mediated recombination led to a loss of mRNA expression in the liver and brain of homozygous mutant mice. (J:243657)