A 3.47 kb mouse Gnrh1 promoter fragment, along with 23 bp of exon 1 of the gene drives expression of a humanized GFP expression unit. An SV40 splice donorsplice acceptor intron and polyadenylation signal are included in the transgene construct. Three lines of mice were generated. (J:126466)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count