A 3.47 kb mouse Gnrh1 promoter fragment, along with 23 bp of exon 1 of the gene drives expression of a humanized GFP expression unit. An SV40 splice donorsplice acceptor intron and polyadenylation signal are included in the transgene construct. Three lines of mice were generated. (J:126466)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x DBA
--
Insertion
--
--
--
38

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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